Macromolecule

There are many substances especially biomolecular and synthetic polymers which have their single molecules so large that they form colloidal solution directly in the solution. These molecules are termed as macromolecules. In case of the simple molecules, the molecular weight is simply the sum of the atomic weights of the atmospresent and each molecule have molecular weight but in case of macro molecule, all molecules may not have same chain and hence molecular weight. So the molecular weight of such molecules are taken as the average of the molecular weight of different chains.

Macromolecules

According to the IUPAC standard definition macromolecules is a single molecule which is used in polymer sciences. In the solution of macromolecules high concentration may alter the reaction rate and equilibrium constant such types of effect is known as molecular crowding. Plastic, Synthetic fibers, synthetic rubber, graphene are some examples of macro-molecules.

Determination molecular weight of macromolecules :

There are several ways to determine the molecular weight of macro molecules some of them are discussed under following topics:

1. From Osmotic Pressure method
2. From Viscosity measurement
3. Sedimentation method